Abstract Search

ea0032p990 | Thyroid (non-cancer) | ECE2013

Postprandial studies uncover differing effects on HDL particles of overt and subclinical hypothyroidism

McGowan Anne , M Widdowson William , O'Regan Anna , S Young Ian , Boran Gerard , McEneny Jane , Gibney James

Overt hypothyroidism (OH) and more controversially subclinical hypothyroidism (SCH) are associated with abnormal lipid metabolism and endothelial dysfunction under fasting conditions. Little data exists regarding the metabolic and vascular effects of OH or SCH under postprandial conditions.We aimed to characterize postprandial metabolism with emphasis on intestinally derived lipoproteins, HDL-cholesterol (HDL-C) and endothelial function in patients with ...

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ea0013p130 | Growth and development | SFEBES2007

The effects of lipid-supplemented total parenteral nutrition (TPN) on hepatic and lipoprotein lipase activity in a premature neonatal piglet model

Hyde Matthew J , Amusquivar Encarnación , Laws John , Corson Anne M , Geering Richard R , Lean Ian J , Putet Guy , Dodds Peter F , Herrera Emilio , Clarke Lynne

We have previously shown that premature piglets maintained on TPN develop fatty livers, but the underlying mechanisms associated with this response in unknown. The aim of the experiment was to use a piglet model for the premature human neonate on TPN to investigate lipase activity in key tissues.Piglets were delivered, by Caesarean, two days prematurely. Bilateral jugular catheters were surgically inserted within 6 hours of birth. Six control piglets wer...

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Endocrine Abstracts

Postprandial studies uncover differing effects on HDL particles of overt and subclinical hypothyroidism

The effects of lipid-supplemented total parenteral nutrition (TPN) on hepatic and lipoprotein lipase activity in a premature neonatal piglet model

BiosciAbstracts